The University of Central Greece was founded in 2003. It is a completely self-administrated institution, under the superintendence of the Greek State, which is exercised by the Minister of National Education and Religions. Its foundation aims at the regional growth and decentralization of the Greek Higher Education, and also at responding to social, cultural and developmental needs of the regional community of Central Greece. The Administrative building of the University of Central Greece is located on 2-4 Papasiopoulou street, in Lamia.

The Department of Computer Science and Biomedical Informatics is operating since the academic year 2004-2005. It is a leading Department in the scientific field of Applied Sciences, as it comes to cover the existing gap in the area of specialization in applications of Informatics in Medicine, Health and Biology.   

The Department of Computer Science and Biomedical Informatics operates in the framework of the “Operational programme for Education and Initial Vocational Training II (O.P.Education)” (ΕΠΕΑΕΚ), named “Tertiary Education Enlargement - University of Central Greece (2004-2006)”, integrated in the Category of projects 2.2.b. “Higher Education Enlargement”, of the Action 2.2.2. “Completion of enlargement and curricula reformation in tertiary education”, with project code MIS 92108. The UCG is the ultimate beneficiary of the project. The Legal Act of the project integration is co-financed by the European Social Fund at 75% and by National Resources at 25%. The managing authority of the project financing is the Ministry of National Education and Religious Affairs (ΣΑΕ 445/3).

Furthermore, the Department of Computer Science and Biomedical Informatics has been integrated into the Measure 5.2 of the “Operational programme for Education and Initial Vocational Training II (O.P.Education)” (ΕΠΕΑΕΚ), named “Equipment for supporting the European Social Fund projects regarding the enlargement of the new Departments of Tertiary Education, Third phase (2004-2006) UCG-European Regional Development Fund” with the code MIS 98671. The Financial Services have been prescribed as the Managing Authorities of this project.